The Essential Guide to Skincare Ingredients: What to Use and Avoid

Brandi Gregge holding a bottle of Youth Serum by M&N.

In the world of skincare, it can feel overwhelming to decipher ingredient lists, understand what works best for your skin, and avoid potentially harmful combinations. We know all too well the discomfort that comes with using a product that causes irritation or a negative reaction. That’s why we’re here to help! We have created a guide that will help you break down the basics, giving you the tools to make informed decisions for healthier, glowing skin.

What to Look For in Skincare Products

Hyaluronic Acid. This powerhouse ingredient hydrates and plumps the skin by attracting moisture. Ideal for all skin types, especially dry and sensitive skin, hyaluronic acid helps maintain the skin's natural moisture barrier.

Vitamin C. Known for its brightening properties, Vitamin C is an antioxidant that protects against environmental damage and helps reduce hyperpigmentation. Look for stable forms like L-Ascorbic Acid, Tetrahexyldecyl Ascorbate, Sodium Ascorbyl Phosphate, or Magnesium Ascorbyl Phosphate for better efficacy. These forms are effective at delivering Vitamin C’s benefits, including brightening the skin, reducing dark spots, and enhancing overall skin health.

Niacinamide (Vitamin B3). A favorite for soothing redness, improving skin elasticity, and  regulating oil production, niacinamide works well for sensitive or acne-prone skin. It's gentle and pairs well with most ingredients.

Peptides. Peptides stimulate collagen production, helping to firm and smooth the skin. They can reduce the appearance of fine lines and wrinkles over time, making them a key anti-aging ingredient.

What to Avoid in Skincare Products

Parabens. Parabens are preservatives commonly found in cosmetics, but they have been linked to hormonal disruptions and allergic reactions. Look for "paraben-free" labels on your skincare. (All of Mint & Needle’s products are paraben-free.)

Fragrance. Added fragrance, whether natural or synthetic, can cause irritation and allergic reactions, especially for sensitive skin. Opt for fragrance-free products whenever possible.

Sulfates. Sulfates are detergents often found in cleansers and shampoos. While they create a rich lather, they can strip the skin of natural oils, leading to dryness and irritation. Look for sulfate-free cleansers for a gentler clean. (All of Mint & Needle’s products are paraben-free.) 

Alcohols (Denatured, Isopropyl). Some alcohols, like denatured alcohol or isopropyl alcohol, can dry out the skin and disrupt its barrier. Be cautious when selecting toners or lotions with these ingredients, especially if you have dry or sensitive skin.

Ingredients You Shouldn't Mix

Vitamin C and Retinol. Vitamin C is most effective at a lower pH, while retinol requires a higher pH to work. Since they work best at different pH levels, using them together can sometimes lead to irritation. To avoid this and maximize efficacy, it's best to separate them in your routine—use Vitamin C in the morning and retinol at night.

AHAs/BHAs and Retinol. Alpha and beta hydroxy acids (like glycolic or salicylic acid) are exfoliants, and combining them with retinol can lead to over-exfoliation, irritation, and redness. If you have more sensitive skin, this combination is especially likely to cause irritation. It’s best to stick to one exfoliant per routine and alternate between them on different nights to minimize the risk of irritation.

Benzoyl Peroxide and Retinol. Benzoyl peroxide, often used to treat acne, can deactivate retinol, reducing its effectiveness. If you need both in your routine, use benzoyl peroxide in the morning and retinol at night.

Navigating skincare ingredients doesn't have to be complicated (though it seems to be). By focusing on ingredients that nourish and protect—like hyaluronic acid, Vitamin C, and peptides—you can build an effective routine that supports your skin’s health. At the same time, being aware of potential irritants such as parabens, sulfates, and fragrances will help you avoid unnecessary damage. Learning which ingredients should be used separately, like retinol and Vitamin C, can prevent irritation and ensure your products work as intended. With the right knowledge, you'll be well on your way to healthy, radiant skin.

When you shop our medical grade skincare products, you can feel confident knowing exactly what you’re putting on your skin. You can find ingredient lists and a breakdown of which skin types a product is best suited for, right when you click on a specific product. And if you have questions, our team is here to help!